Understanding pain mechanisms: RNA expression analysis of peripheral nervous system tissue
Learn about the technical aspects and challenges to using RNAscope technology for RNA expression analysis on rodent and human dorsal root ganglion (DRG)
9 Jun 2020Expert insights
Learn how novel RNA in situ hybridization technology, RNAscope®, can be applied to the analysis of human and rodent peripheral nervous system tissue to better understand the molecular mechanisms of pain.
In this SelectScience webinar, Prof. Theodore Price and Dr. Stephanie Shiers, of the Department of Neuroscience and Center for Advanced Pain Studies at University of Texas at Dallas, will discuss technical aspects and challenges to using RNAscope® technology for RNA expression analysis on rodent and human dorsal root ganglion (DRG).
Dr. Shiers will describe her extensive experience working with human tissues from organ donors and how RNAscope can be used to gain molecular insight into pain mechanisms in humans. Prof. Price will discuss recent advances in understanding how viruses might interact with the peripheral nervous system to cause pain or exacerbate viral disease.
Register NowKey learning objectives:
- Human and mouse sensory neuron populations are distinct — which has important implications for pain mechanisms
- Type I interferons act directly on DRG neurons and increase their excitability
- RNAscope technology is a useful tool for analysis of human and rodent peripheral nervous system tissue
The live webinar takes place on Wednesday, June 24, 2020, at:
- 18:00 BST
- 19:00 CEST
- 10:00 PDT
- 13:00 EDT
Register to watch the full webinar here>>
SelectScience runs 3-4 webinars a month across various scientific topics, discover more of our upcoming webinars>>
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RNAscope™ Technology
Advanced Cell DiagnosticsIndependent of your genes of interest, thes easy RNA in situ hybridization assays use common reagents and protocols; providing universal assay conditions. All RNA-ISH kits contain reagents in a convenient ready-to-use (RTU) format, and chromogenic dyes are available to interrogate a single or two genes simultaneously. Most versatile are the RNAscope Multiplex Fluorescent Reagent Kits, enabling you to interrogate 1, 2 or 3 genes simultaneously.