Waters Introduces LiveID Software for Real-Time, Direct-from-Sample Food Analysis and Plant Phenotyping

Direct sample classification by mass spectrometry speeds creation of test results and decision-making

7 Jun 2017
Weylan Kiam-Laine
Microbiologist

Waters Corporation has introduced its new LiveID™ Software for near- instantaneous, direct-from-sample measurement and classification of food products including meat and crops by Waters’ quadrupole, time-of-flight (QTof) mass spectrometers. The new software enables Waters® Xevo® G2-XS QTof or SYNAPT® G2-Si Mass Spectrometers equipped with an iKnife™ Sampling device, Rapid Evaporative Ionization Mass Spectrometry (REIMS™) ion source and MassLynx® Mass Spectrometry Software to help laboratories detect food fraud. Waters LiveID Software is now available on a worldwide basis.

“Information on food samples separated in time and space from where it is needed most isn’t efficient and hurts productivity. We’ve designed LiveID Software to make the process of getting real-time information about samples as intuitive, as quick and as easy as possible,” said Ronan O’Malley, Senior Director of Informatics Products, Waters Corporation.

Food fraud - when food is labeled and sold as something that it is not - is a growing and pernicious problem that funds organized crime, cheats consumers and jeopardizes the reputation of food producers and the health of economies dependent on food exports.

In recent years, QTof mass spectrometry has emerged as a promising technique for detecting food fraud. One who has pioneered its use for this application is Professor Chris Elliott, Director – Institute for Global Food Security, Queens University Belfast. “The REIMS QTof technology platform has the potential to revolutionize food authenticity analysis due to its speed and ability to detect multiple issues simultaneously that impact the integrity of the food we eat. I am not aware of any other technology developments that will provide this level of support to the food industry.”

Faster than conventional techniques like immunosassay and PCR, mass spectrometry enabled by LiveID Software produces definitive results in seconds. With iKnife Sampling and REIMS, no sample pretreatment or separation is typically necessary. When the hand-held iKnife sampling device comes in contact with a sample of animal or plant tissue or other processed foodstuffs such as butter, it creates smoke containing compound-specific molecules which are directed to the REIMS source where the molecules are ionized and then passed on to be detected by the mass spectrometer. In very little time, the LiveID software then creates a molecular profile or chemical fingerprint of the sample, compares it to a user-generated database of reference fingerprints and then classifies the sample as belonging to one of a number of sample types or groupings.

Waters introduced iKnife Sampling and REIMS technologies to its QTof mass spectrometers in 2015. Since then, Waters has evolved the design of the REIMS source to make real-time decision-making using mass spectrometry straightforward and accessible by researchers who wish to explore the potential of the technology.

For more information on the Waters LiveID software, see www.waters.com/liveid

Xevo G2-XS QTof

Waters

Xevo G2-XS QTof - eXtreme Sensitivity, eXtraordinary Selectivity, eXceptional Solutions. For the scientist who needs to identify, quantify and confirm the broadest range of compounds in the most complex and challenging samples the Xevo G2-XS QTof provides maximum robustness with no compromise in performance, class-leading real-world quantitative sensitivity, the highest quality, most comprehensive qualitative information, flexibility to adapt to changing needs and is accessible to experts and non-experts alike.

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MassLynx MS Software

Waters

Acquire, Analyze, Manage, and Share Mass Spectrometry Information MassLynx™ Software increases the speed at which you can convert your sample data into valuable knowledge. It provides you with the fundamental platform to acquire, analyze, manage, and share your mass spectrometry information. MassLynx intelligently controls any Waters mass spectrometry system, from sample and solvent management components to mass spectrometer and auxiliary detectors. MassLynx Software may acquire nominal mass, exact mass, MS/MS and exact mass MS/MS data. MassLynx’s Sample List is the core of the system. It maintains and consolidates the data on all of your samples. You also initiate any activities related to your sample from the Sample List. This "sample centric" approach simplifies the interaction with your LC/MS or GC/MS system, acquired data and processed results. Process Application-specific Data MassLynx Software features general purpose and specialized Application Managers that provide information for your specific MS analyses and data. Two come standard with MassLynx: QuanLynx™ for automated quantification included as standard with MassLynx OpenLynx™ for qualitative screening and identification Optional Application Managers can perform: Targeted quantitative analysis Mass-directed purification Metabolite identification Deconvolution of complex chromatograms Metabonomics & metabolomics Protein identification and protein characterization

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