Thermo Fisher Scientific collaborates with Protein Metrics to optimize data analysis in biopharma

Protein Metrics’ software solutions complement Thermo Fisher’s mass spectrometry systems to facilitate precise, reliable data processing and drive innovation

24 Mar 2021
Cameron Smith-Craig
Cameron Smith-Craig
Pharma and Applied Sciences Editor

Industry news

Thermo Fisher Scientific, a world leader in serving science, and Protein Metrics, a developer of world-class software tools for protein characterization, have entered into a non-exclusive co-marketing agreement to provide advanced mass spectrometry data processing and analysis capabilities to drive innovation across the full spectrum of biopharmaceutical and proteomics applications, from research and development to quality control.

Thermo Fisher brings the cloud-enabled Thermo Scientific Chromeleon CDS software to this collaboration, providing biopharmaceutical and proteomics scientists with superior automation and workflow support to help achieve productivity gains of up to 33%. Easily integrated into company systems and seamlessly scaled from workstation to global enterprise deployment, the Chromeleon CDS software ensures business continuity. The software allows operation from remote locations across global laboratory networks, reducing administrative costs and providing resourcing flexibility.

Supporting this collaboration, the Protein Metrics Byos platform for protein characterization enables researchers to move from raw data files to reporting in just minutes, allowing post-translational modifications and other critical quality attributes to be monitored with speed and efficiency. In addition, customers can also take advantage of Protein Metrics’ private-cloud Byosphere enterprise platform, which delivers enterprise-level capacity for automation, collaboration and data management in a single platform for GxP and non-GxP environments.

"Scientists undertaking biopharmaceutical and proteomics applications are challenged daily with having to accurately and reliably process a wealth of data derived from mass spectrometry instruments, which can be time-intensive and error-prone," said Matt Hazlewood, senior director, global chromatography data systems, Thermo Fisher Scientific. "Our collaboration with Protein Metrics allows us to leverage our shared expertise and seamlessly integrate our compliance-ready software capabilities to offer customers flexible tools that address these challenges and help meet their need for advanced technologies that analyze their mass spectrometry data."

“We are proud that our proven biopharmaceutical solutions enable companies worldwide to analyze and report on complex biotherapeutics,” remarked Eric Carlson, PhD, president and CEO, Protein Metrics, Inc. “Byosphere, resting on Byos' solid foundation, delivers to our users a single platform for GxP and non-GxP environments. Integrating with critical enterprise data systems, such as Chromeleon CDS, we aim to provide our mutual biopharmaceutical customers with intuitive, streamlined workflows to manage the burgeoning volume and complexity of analytical data with confidence.”

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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.ProteomicsProteomics refers to the analysis of proteins through a variety of different experiments in order to understand structure and functionality. Typical techniques include protein purification and mass spectrometry.
Thermo Fisher Scientific collaborates with Protein Metrics to optimize data analysis in biopharma