Tahoe Therapeutics generates large single-cell atlas using INTEGRA Biosciences' automated pipetting technologies

Tahoe Therapeutics aims to use the speed and accuracy of these automated systems to generate a dataset fifty times larger than its already record-breaking Tahoe 100 million single-cell atlas

16 Feb 2026
Team at Tahoe Therapeutics

Team at Tahoe Therapeutics. Photo courtesy of Tahoe.

Tahoe Therapeutics – a biotech start-up based in San Francisco, California – is creating the largest ever atlas of cell-chemical interactions to inform drug discovery.

Combining automated pipetting systems from INTEGRA Biosciences with Parse Biosciences’ Evercode™ single-cell RNA sequencing (scRNA-seq) products, and its own proprietary AI algorithms, the company already has several drug discovery programs running in parallel across multiple cancer types, and is expanding into other therapeutic areas.

Workflow automation is essential for the Tahoe Therapeutics team’s aim of generating some of the largest scRNA-seq datasets in the world. The company invested in an ASSIST PLUS pipetting robot with a VIAFLO handheld electronic pipette to automate its research workflows.

INTEGRA’s partnership with Parse Biosciences means these tools work seamlessly with the Evercode products to provide a validated, turnkey solution covering every stage of scRNA-seq sample preparation. These tools enable the company to scale up its operations while improving reliability and reducing hands-on time by up to 75 percent.

Tahoe Therapeutics aims to use the speed and accuracy of these automated systems to generate a dataset fifty times larger than its already record-breaking Tahoe 100 million single-cell atlas.

Johnny Yu, Co-founder and Chief Scientific Officer at Tahoe Therapeutics, explained, “Automation with the ASSIST PLUS has increased our throughput for single-cell preparation more than 5-fold. The most important thing is that it’s highly accurate: you’re not relying on the inherent variability of manual processing. The combination of INTEGRA’s instruments and Parse Biosciences’ kits allows us to leapfrog many biopharmaceutical companies and generate larger datasets using less instrumentation, reagents and capital.”

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VIAFLO Electronic Pipettes

INTEGRA Biosciences

Electronic pipettes with touch wheel user interface.   VIAFLO pipettes accommodate any pipetting task at hand: from single transfers to complex protocols. An intuitive touch wheel interface and color display allows for the quickest volume changes and user friendly menu navigation. The ergonomic design enables effortless pipetting. The unique tip fitting of the VIAFLO pipette assures that GripTip pipette tips will never loosen, leak or fall off. VIAFLO Electronic Pipettes Features:   GripTip Pipette Tips - By designing our GripTips™ in tandem with VIAFLO pipettes, we have created a unique, integrated system that offers the securest pipette and pipette tip connection. High lateral resistance. This prevents tips from falling off when touching off a multichannel pipette within a 96 or 384 well plate. Low required tip attachment forces. Low required tip ejection forces. All tips seal at the same height ensuring a perfect touch off and increased precision when dispensing. Intuitive User Interface - A full color screen and a proven touch wheel interface offer quick and comprehensible menu navigation. Simply by moving a finger over the touch wheel, menus and settings can be accessed. All menus are spelled out on the clear to read screen making memorizing of abbreviations unnecessary. Convenient Pipette and Program Management - VIAFLO pipettes can be connected to a computer via USB port. With the free to use pipette management software VIALINK, custom programs can be created on the computer and then be transferred onto VIAFLO pipettes. For laboratories with many users or power users with many pipetting protocols, all custom programs can be stored and backed up in a library on the computer. Applications: Repeat Dispense Manual Pipetting Sample Dilution Reverse Pipetting Variable Dispense

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