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SRU Biosystems Introduces Label-free Instrument & Applications for Stem Cells at SBS 2010

5 Apr 2010
Sarah Sarah
Marketing / Sales

Product news

SRU will feature the first-of-its-kind label-free, high resolution reader, the BIND® SCANNER, at booth 710. The BIND® SCANNER is designed for low cell number, high throughput primary and stem cell assays such as cytotoxicity, chemotaxis and differentiation. The SCANNER will also be featured in a technical workshop on Tuesday, April 13th at 8:00am as well as in several scientific posters.

Also in SRU’s booth will be 2 other label-free BIND Readers ideal for low to high throughput biochemical and cell-based applications. Stop by and discuss your application needs with our scientific booth staff or pick up information about our latest applications including cytotoxicity, chemotaxis, ion channel and GPCR profiling assays.

Booth 710

New Products:
The BIND SCANNER® for label-free, primary cell, stem cell and low cell number assays requiring well below 1,000 cells per well.

Tutorial:
Tuesday, April 13th, 8:00-8:45am
Room 129B
Demonstration of Novel GPCR & Stem Cell Activity using BIND® Label-free Technology.
• Initial Characterization of Partial Agonists Using Label-Free BIND Technology. Dr. Scott Perschke, Caliper Discovery Alliances & Services (CDAS), USA
• Label-free Stem Cell Assays: Chemotaxis, Differentiation and Cytotoxicity using the new BIND SCANNER. Dr. Steven Shamah, SRU Biosystems, USA

Wednesday, April 14th, 1:30-2:15pm
Room 129B
Recent Advances in Cell Adhesion and Platelet Activation Label-free Assays.
• Identification of compounds that inhibit cell adhesion using BIND label-free technology. Dr. Michael Bova, Elan Corporation, USA
• Detection of platelet adhesion and activation-related morphological changes on the SRU BIND® Reader. Dr. Yuval Blat, Bristol-Myers Squibb, USA

Posters
• High-Throughput Label-free, BIND® Assays for Monitoring Stem Cell Differentiation
• Chemotaxis in High-Throughput: Label-Free and Transwell-Free BIND® Assays
• Profiling Compound Toxicity using Label-Free BIND® Technology from SRU Biosystems

Tags

Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.

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