Scientists’ Choice Awards Winners Announced for Drug Discovery & Development

Bruker Daltonics and AstraZeneca among those recognized during prestigious ceremony at SLAS2017

7 Feb 2017
Sarah Thomas
Associate Editor

Editorial article

Scientists’ Choice Awards® winners and nominees celebrate at SLAS2017

SelectScience® is delighted to announce the winners of the 2017 Scientists’ Choice Awards® for Drug Discovery & Development, as chosen by scientists across the world. Winners and nominees were celebrated during a special ceremony held on February 6 at the SLAS2017 international conference and exhibition in Washington D.C., USA. Read on to discover the winners of these coveted awards and highlights from this exciting event.

The Scientists' Choice Awards® The annual Scientists' Choice Awards® celebrate the laboratory products and manufacturers that make a difference to the industry. Scientists are invited to nominate, vote and review online.

Best New Product of 2016

SelectScience revealed the Bruker Daltonics rapifleX™ MALDI PharmaPulse™ as your chosen winner for Best New Drug Discovery & Development Product of 2016, as nominated and voted for by scientists around the globe.

Dr Meike Hamester, Director Small Molecule Pharma Business, Bruker Daltonik GmbH, accepted the award for Best New Drug Discovery Development Product of 2016

Do you use this system? Let us know what you think by reviewing the Bruker Daltonics rapifleX™ MALDI PharmaPulse™ today.

Runners Up

 

Best Drug Discovery Video Interview of the Year

Jonathan Wingfield, Principal Scientist, and Steve Rees, Vice-President of Screening Sciences and Sample Management, AstraZeneca

An interview with AstraZeneca’s Vice-President of Screening Sciences and Sample Management, Steve Rees, and Principal Scientist, Jonathan Wingfield, was your chosen winner for Best Drug Discovery Video Interview. Watch the video to learn about a breakthrough workflow that combines acoustic liquid handling technology, from Labcyte Inc., and mass spectrometry to produce high quality data, increase throughput and reduce both assay development and screening costs by 100- to 1000-fold.

Best Drug Discovery & Development Article of the Year

The McManus Lab Image: Courtesy of Dr Kirk McManus

The Scientists' Choice Award for Best Drug Discovery & Development Article was awarded to an interview with Dr Kirk McManus, Associate Professor in the Department of Biochemistry & Medical Genetics at the University of Manitoba and Senior Scientist within the Research Institute in Oncology at CancerCare Manitoba. Read the article to learn about cutting-edge cancer research using a high throughput screening workflow from BioTek Instruments, Inc. that aims to identify cancer causing genetic abnormalities and screen potential therapies.

Commenting on the award, Dr McManus told SelectScience:

“It is with great pleasure that I accept this award and honor on behalf of my research team at CancerCare Manitoba and the University of Manitoba. It was truly a pleasure to provide insight into the cancer research and high throughput screens we are performing and share this with a world-wide audience. I would also like to take this opportunity to thank Select Science, and in particular Sarah Thomas and Lynsey Forsyth, for the professional manner in which they conducted the interview and the outstanding article they produced. Finally, I would also like to thank the BioTek team, Charles Amirmansour, Chris Wilson and Brad Larson, for keeping us up and running, and assisting in the development of new and innovative screens.”

Peter Banks, Ph.D, Scientific Director, BioTek Instruments, Inc., accepted an award recognising the use of the company's technology in research by Dr McManus' laboratory

Reviewers' Choice Award for Drug Discovery & Development Product of the Year

The Reviewers' Choice Award for Drug Discovery & Development Product of the Year, which is based on the reviews published on the SelectScience website, was won by BioTek Instruments, Inc. for its Synergy™ Neo2 Multi-Mode Reader.

Briar Alpert, President, BioTek Instruments, Inc., accepted the Reviewers' Choice Award for Drug Discovery & Development Product of the Year

Visit the Scientists' Choice Awards website for more information.

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Capillary ElectrophoresisCapillary electrophoresis (CE) is used to separate molecules based on charge, size and hydrophobicity. Pressure, voltage or a vacuum is used to introduce the sample to fused silica capillaries. Fluorescence, UV/Vis, UV or diode array detectors are used to visualize components. Types of CE systems include capillary electrochromatography (CEC), capillary zone electrophoresis and capillary gel electrophoresis. Find the best capillary electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. 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Equipment used for quantitative analysis includes Fourier-transform infrared (FTIR) spectrometers, infrared cameras, FTIR gas analyzers, as well as attenuated total reflectance (ATR) accessories and pellet or film presses. Find the best IR spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. NMR and EPR SpectroscopyNuclear magnetic resonance (NMR) spectroscopy is used to resolve the local chemical environment of atomic nuclei with spin, revealing information on molecular structure, dynamic processes and chemical reactions of organic molecules, from proteins to synthetics. Electron paramagnetic resonance (EPR) also known as electron spin resonance (ESR) spectroscopy is used to detect and quantify paramagnetic species in a sample, including free radicals as transition metal ions. By immersing the sample in a strong magnetic field, both NMR and EPR spectrometers probe the sample with either radio waves or microwaves respectively. A range of benchtop, solid-state and time domain NMR spectrometers & EPR spectrometers are available, as well as NMR tubes, NMR solvents, software, coils, and magnets. Find the best NMR & EPR equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.UV-Visible SpectroscopyUltraviolet-visible (UV-Vis) spectrophotometers are used to measure the interaction of UV and visible light with a sample, including transmission, reflectance & absorbance. The two major instrument classes are single-beam or double-beam spectrophotometers. More specialized equipment includes colorimeters, spectroradiometers and refractometers. Portable and microvolume spectrophotometers are also available. For the modular spectroscopy lab, explore a range of light sources for combination with a spectrograph/spectrometer and optics. Find the best UV-Vis spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Western BlottingWestern blotting equipment is used to transfer and identify specific proteins within a sample, reveal protein modifications, as well as give a semi-quantitative estimation of their concentration. Western blotting equipment includes all apparatus necessary to transfer proteins from gel to membrane and subsequent processing steps. Protein transfer can be performed by electroblotting with wet, semi-dry and dry transfer systems onto nitrocellulose and PVDF membranes. Blocking, washing and labeling of membranes follows, involving buffers, blocking reagents, blotting / incubation trays, labeling reagents, immunoblotting assays, antibodies and conjugates. Automated equipment for these steps is available to accelerate your lab workflow. Finally, detection and imaging of proteins can be conducted using gel documentation and imaging systems. Find the best western blotting equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Adhesion AssaysCell adhesion assays are used to quantitate attachment and analyze the molecular mechanisms for extracellular matrix adhesion, cell migration and sensitivity to inhibitors. Find the best cell adhesion assay equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Scientists’ Choice Awards Winners Announced for Drug Discovery & Development