Salt Tolerant Interaction Chromatography Membranes
2 Dec 2011Sartobind STIC® membranes are a new group of Salt Tolerant Interaction Chromatography membrane adsorbers from Sartorius. With the primary amine ligand they bind negatively charged impurities such as DNA, host cell proteins, endotoxins and viruses at much higher salt concentrations than known from conventional Q matrices.
Sartobind STIC membranes eliminate the need for feedstream dilution before flowthrough polishing of recombinant proteins and Mabs. The single use product reduces validation cost, consumption of buffers, and speeds up the time it takes to bring products to market. The Sartobind STIC family scales linearly within the Sartobind SingleSep formats of Sartobind pico with 0.08 ml membrane volume up to Sartobind mega with 1.6 liter.
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Sartobind STIC® salt-tolerant membrane chromatography
Sartorius GroupDisposable capsules with salt tolerant interaction membranes for polishing in biomanufacturing. The Sartobind STIC® adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines. Plug and play device Can be used like a filter Enhanced flexibility Reduces validation costs Recommended flow rate of up to 30 bed volumes/min