Prodesse, Inc. and Invitrogen Collaborate on First Molecular Diagnostic LUX™ Products

20 Jul 2006

Product news

Prodesse, Inc., a Wisconsin-based global leader in Multiplex PCR, and Invitrogen Corporation, a provider of essential life science technologies for disease research and drug discovery, today announced the signing of a license agreement for the first diagnostic assays with Invitrogen's LUX™ technology.

Utilizing Prodesse's global distribution capabilities the partnership positions Invitrogen's technologies in new market segments, serving a new customer base.

LUX™ (Light Upon eXtension) reagents are an essential starting point for a broad scope of drug discovery and molecular diagnostic applications including gene expression studies, biomarker analysis and functional genomics experiments. By providing improved sensitivity and specificity over traditional methods of analysis and the ability to examine multiple targets in one experiment, LUX™ was developed to meet the demanding needs of these varied applications.

"As we continue to rapidly increase our real-time products menu, access to Invitrogen's LUX™ platform is an important milestone," said Tom Shannon, President & CEO of Prodesse. "Now we can provide our customers with a technology that has significant design flexibility as well the tremendous advantage of conveying service rights that do not carry royalty burdens to end users."

"Invitrogen's partnership with Prodesse is a natural evolution of our proven technology platforms and allows us to better serve our customers through collaborations with innovative diagnostic providers," said Gregory T. Lucier, Chairman and CEO of Invitrogen Corporation. "Scientists in basic research and drug discovery and development have already found our LUX technology to produce more reliable data than many of the other quantitative PCR chemistries available. Our partnership will broaden the reach of this technology into clinical laboratories around the world."

Licensing and cost constraints have limited many companies in the molecular diagnostics market. Invitrogen's unique technologies enable companies like Prodesse to provide their customers with state-of-the-art molecular diagnostic products. Invitrogen's LUX™ technology, combined with SuperScript® III Reverse Transcriptase and the new Platinum® Tfi DNA Polymerase, provides a powerful and complete solution for assay development.

For additional information, please visit Prodesse at booth # 106 and Invitrogen at booth # 2071 and 2072 at the American Association of Clinical Chemistry (AACC) Annual Lab Expo July 23-26, 2006 in Chicago, IL. AACC is an international scientific/medical society of clinical laboratory professionals, physicians, research scientists and other individuals involved with clinical chemistry and related disciplines. Founded in 1948, the society has 10,000 members and is headquartered in Washington, DC.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.
Prodesse, Inc. and Invitrogen Collaborate on First Molecular Diagnostic LUX™ Products