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PEGS Europe 2016: Nanotemper Demonstrates the Prometheus NT.Plex Live on Stage

NanoTemper Technologies
17 Nov 2016
Lois Manton-O'Byrne, PhD
Executive Editor

Product news

This year at PEGS Europe in Lisbon, NanoTemper Technologies, a leader in biomolecular analysis products, carried out the first ever live instrument demonstration on stage to visualize perfect ease-of-use of the Prometheus NT.Plex instrument.

They also presented application examples from biopharma and biotech industry to show how Prometheus helped to reduce time and money in development.

Prometheus NT.Plex is based on nanoDSF technology for easy, rapid and accurate analysis of protein folding and stability. nanoDSF is an advanced dye-free Differential Scanning Fluorimetry method for measuring ultra-high resolution protein stability. By analyzing changes in the fluorescence of the amino acids tryptophan or tyrosine, chemical and thermal stability is assessed in a truly label-free approach. The dual-UV technology by NanoTemper allows on-the-fly fluorescence detection, providing unmatched scanning speed and data point density. This results in ultra-high resolution of unfolding curves, which are not compromised by aggregation thus allowing detection of multiple, and even minute unfolding signals.

Watch the live demonstration

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NanoTemper TechnologiesCompany website

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.BiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.BiotechnologyBiotechnology is the use of biological processes, organisms, or systems in the production of products and services. It spans a wide range of applications, including healthcare, agriculture, and environmental management. Browse our peer-reviewed product directory to find the best biotechnology tools, compare products, check reviews, and get pricing directly from manufacturers.Protein Stability

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PEGS Europe 2016: Nanotemper Demonstrates the Prometheus NT.Plex Live on Stage