No compromise, no limits, no doubt: The ultimate in micro and macro fluorescence observation

8 Jun 2006

Product news

The unique Olympus MVX10 MacroView combines maximum detection sensitivity at the lowest magnifications with a high magnification zoom for the resolution of fine details within small organisms, organs, tissues and even cells.

This enables researchers to clearly see fluorescent images of whole organisms right down to the cellular level with unprecedented brightness, resolution and precision.

From low magnification confirmation of e.g. gene expression in whole organisms, such as zebra fish (D. rerio) or C. elegans, to detailed observation of expression in cells at high magnification, the MVX10 is ideal for a wide range of uses. With smooth, stepless 10x zooming (0.63 to 6.3), the MVX10 delivers brightness and resolution beyond the capabilities of conventional fluorescence stereo microscopes. This eliminates the need for switching between a stereomicroscope and inverted or upright compound microscopes during fluorescence screening procedures, such as gene expression.

Unlike standard stereo microscopes with two optical paths, the MVX10 is a mono-zoom microscope which uses a single, large-diameter optical path optimised to collect the weak light generated by fluorescence at all magnifications. This optical path, with specially designed lenses, provides an exceptionally high NA (Numerical Aperture) enabling the unique brightness and increased resolution, whilst retaining the working distance and wide field of view as all stereo microscopes. This also ensures easy observation of dynamic processes over time.

All components of the light path contribute to the phenomenal fluorescence performance of the MVX10. Using the latest technologies and new materials, the MVX10 objectives produce low autofluorescence. Together with the extremely high NA, this results in an exceptionally good signal-to-noise (S/N) ratio, ensuring excellent contrast for observation of even the faintest fluorescence signals.

The peerless attributes of all the optical components mean that specimens can be exposed to fluorescent light for shorter periods, thereby minimising the risk of photo bleaching, or even cell damage. This is also true at near-infrared wavelengths where the MVX10 has superior transmission properties - also increasing the range of useable fluorophores.

Fully compatible with a wide range of photography units, illuminators and stands, the MVX10 MacroView also optimises recorded fluorescence images at high magnification when using high performance digital cameras.

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Fluorescence SpectroscopyFluorometers and spectrofluorometers (also called fluorescence spectrometers) are used to measure the intensity and wavelength of fluorescent light emitted from a sample after excitation by illumination. Spectrofluorometers utilize monochromators to select the desired wavelengths, whereas filter fluorometers employ a set of filters. Spectrofluorometers for measuring steady-state fluorescence and lifetime fluorescence (or time-resolved fluorescence) are available, as well as fluorescence microscopes and microplate readers. Find the best fluorescence spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
No compromise, no limits, no doubt: The ultimate in micro and macro fluorescence observation