Next Generation Single-Use Bioreactor Improves Cell Culture Performance
18 Sept 2013
The next-generation HyPerforma Single-Use Bioreactor has been redesigned to provide improved ergonomics while retaining traditional stainless steel bioreactor design principles to enhance cell culture performance.
The next generation bioreactor -- Thermo Scientific HyPerforma Single-Use Bioreactor (S.U.B.) -- offers all of the advantages of previous S.U.B.s while offering advancements that make it easier to manage tubing systems and loading of single-use Thermo Scientific bioprocess containers, as well as faster heat up and cool down, flexible positioning, and height-adjustable single- or dual-filter brackets.
The new line also offers a smaller footprint to optimize space and a cable management tree to reduce clutter in the production labs. A vertical access door on larger S.U.B.s also simplifies the bioprocess container loading process.
“We have gained experience and worked closely with our customers to develop a next-generation single-use bioreactor that matches performance of its predecessors while providing even better usability,” said Millie Ullah, senior product manager for single-use systems at Thermo Fisher Scientific. “The initial feedback from our customers has been overwhelmingly positive.”
Thermo Fisher showcased its new S.U.B systems this week at the BioProcess International Conference and Exhibition, September 17-19, 2013, Hynes Convention Center, Booth # 611.
The six available sizes (50L, 100L, 250L, 500L, 1000L and 2000L) can be integrated with a choice of control systems either as an open architecture solution or a turn-key system that is shipped with a dedicated controller from Finesse or Applikon. The supported software platforms include PC, Delta V, EZ, Allen Bradley and Siemens (PLC) to give customers a broad range of choices for cGMP and non-cGMP manufacturing.
In 2006, Thermo Fisher launched the first stirred-tank single-use bioreactor (SUB) and today more than 85 percent of the top biopharma companies employ Thermo Scientific HyPerforma bioreactors. Available in six sizes from 50-2000L, the bioreactor is known for providing consistent results from small to large scale cell culture processing.
Related Products
Request Quote for All Products
HyPerforma™ S.U.B. TK 250L Single-Use Bioreactor
Thermo Fisher ScientificThe Thermo Scientific™ HyPerforma S.U.B. TK 250L system combines the experience of hundreds of single-use stirred-tank bioreactors used in the industry today with a state-of-the-art controller system for a turnkey bioprocessing solution.This out-of-the-box solution dramatically shortens implementation time and reduces upfront cost while providing all the advantages of our open-architecture single-use bioreactors (S.U.B.). HyPerforma™ S.U.B. TK 250L Single-Use Bioreactor Features: A complete single-use, stirred-tank bioreactor system with designated controller. Vessel is designed in industry-proven classical geometry and tank design. Single-use bioprocess containers (BPC) are constructed of CX5-14, a robust, flexible polyethylene film material. Pitched-blade impeller mounted on an angled shaft offers consistent mixing without vortexing, avoiding the need for baffles. Complete turnkey system features minimal setup measured in hours instead of days Safety interlocks control agitation, pressure, and temperature. Control platform offers superior functionality and performance "out of the box". Control system has intuitive, user-friendly touch screen user interface. Cable and tubing management system eliminates clutter, allowing you to work and navigate around the system with ease. Easy to clean due to full stainless-steel casing with Nema 4X rating. Small footprint allows maximum floor space efficiency. Graduated viewing window enables volume indication. Complete gassing system includes 6 x MFC. Four variable-speed pumps. Flexible configuration includes right- or left-sided options for vessel and controller unit. Operate both single-use and reusable sensors. Load cells included for accurate weight management.