INTEGRA Announces New Plate Holder to Facilitate 1536-well Pipetting

14 Dec 2016
Lois Manton-O'Byrne, PhD
Executive Editor

INTEGRA has introduced a new plate holder enabling 1536-well pipetting on its VIAFLO 384 electronic handheld pipette. The introduction of this new capability provides screening labs with a unique alternative to fully automated robotic liquid handling systems as the VIAFLO 384 is the only benchtop pipette on the market, which allows easy and precise pipetting into 1536 well plates.

Most screening assays start in larger formats (96 – 384 well plates) before they are up-scaled to the 1536-well plate format. For assay development, fully automation robotic systems are often not the best choice because they are costly, typically complex to use and require long set-up times. In the assay development phase, when not as many plates need to be processed, a quickly adaptable and easy-to-use benchtop pipetting system offers a superior choice.

Pipetting into 1536 well plates is a task requiring accurate liquid handling and precise tip positioning. For optimal alignment of the pipetting head with the target 1536 well plate, the new plate holder is adjustable in the y-direction. The easy to use slide function of the plate holder shifts the 1536-well plate in order to have access to all 4 quadrants with a 384-channel pipetting head. To watch a video on how to use the 1536-well plate holder with the VIAFLO 384, click here.

The VIAFLO 384 is fully compatible with GripTip pipette tips which provide a perfect seal every time and won't fall off during use. To enhance 1536-well pipetting performance, INTEGRA has developed a new 12.5 µl SHORT GripTip pipette tip. This tip was specifically designed for 1536 well pipetting and enables precise targeting of the small wells.

The VIAFLO 384 is a handheld 384-channel electronic pipette that enables fast, precise and easy transfer of 384 samples simultaneously. Uniquely the VIAFLO 384 offers all the benefits of increased sample throughput as well as lower sample and reagent use without the expense of having to invest in a robotic liquid handling system. The VIAFLO 384 has been designed to be used just like a standard handheld pipette. Therefore, no special skills or training are required to operate it. Servo assisted motor steering ensure that operating the VIAFLO 384 is both effortless and precise. The VIAFLO 384 features the company's popular Touch Wheel™ pipette user interface enabling simple and fast programming of a wide range of pipetting modes including repeat dispense, serial dilute and mixing routines. The VIAFLO 384 comes with 10 pre-defined pipetting modes enabling the system to be used productively almost immediately. A further 40 user designated custom programs allow even the most diverse and complex pipetting operations. The VIAFLO 384 can be connected to a PC with VIALINK software enabling easy custom program exchange and firmware upgrades. Labs will immediately benefit from the increased productivity and high precision delivered by a VIAFLO 384.

GripTips for INTEGRA Pipettes

INTEGRA Biosciences

The GripTips together with VIAFLO, VOYAGER and EVOLVE pipettes from INTEGRA form an integral system. Pipette tip and pipette were designed to fit perfectly together. As a result, the loading and attachment forces of the tips could be reduced to minimize wrist related stresses. In addition, the system provides a perfect tip sealing and reliably prevents tips from accidently falling off during pipetting. Consistent and safe pipetting guaranteed! Using Low Retention GripTips from INTEGRAwith heightened hydrophobic properties prevents low surface tension samples from spreading out at the inner wall of the tips for a maximum liquid recovery. Available in five volumes (12.5 µl to 5000 µl) GripTips come in bulk or stackable boxes (non-sterile, sterile and filtered) featuring colour-coded inserts that correspond to the volume ranges of the INTEGRA pipettes. The 12.5 µl and 125 µl GripTips come in 384-fold configuration, so the same tips and boxes can be used with 16-channel pipettes as well. The GREEN CHOICE is an environmentally friendly packaging of GripTips. Each GREEN CHOICE contains five GripTip inserts of non-sterile or pre-sterilized GripTips to refill the current tip boxes. Features and benefits: GripTips snap onto the tip fitting of INTEGRA pipettes, which prevents tips from falling off. Reduced tip attachment and ejection forces for comfortable, stress-free pipetting. Precise and consistent tip seal ensures that all tips on a multichannel pipette are precisely at an identical height for reliable touch offs and consistent pipetting results.

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VIAFLO 384 – Electronic 24, 96 and 384 Channel Handheld Pipette

INTEGRA Biosciences

INTEGRA Biosciences’ VIAFLO 384 increases productivity of sample preparation in microplates and supports 24, 96 and 384 channel pipetting heads. VIAFLO 384 is used like a standard handheld pipette. It is hand-controlled but movements are supported by motors for an effortless workflow and precise targeting of the microplate wells. With a choice of ten interchangeable pipetting heads, the unit quickly adapts to any 24, 96, 384, or even 1536 well pipetting application in a volume range of 0.5 μl to 1250 μl.  VIAFLO 384 benefits from the innovative GripTip system. The special pipette tips, together with the unique tip fitting, form an integral system. It guarantees tips will not fall off during pipetting and provides a reliable sealing of every tip. VIAFLO 384 can be used for sample transfers from reservoir to plate, plate to plate or within plates. VIAFLO 384 Features and Benefits: VIAFLO 384 is used like a handheld pipette and has an intuitive user interface, freeing staff from training time. Pipetting heads can be changed for an optimal instrument adaption to different volume ranges, increasing accuracy and precision. The innovative GripTip system provides a reliable sealing of every tip and guarantees that tips will never fall off, providing safe and reproducible assay preparation. Various pipetting modes are available for increased productivity and application customization.

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