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IncuCyte<sup>®</sup> Live-Cell Analysis Platform Cited In Over One Thousand Publications

16 Jan 2017
Lois Manton-O'Byrne, PhD
Executive Editor

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The IncuCyte® live-cell analysis platform from Essen BioScience has been cited in more than 1000 peer-reviewed publications since its introduction. The publications describe a wide range of applications across a variety of research / therapeutic areas including immuno-oncology, immunology, neuroscience and stem cell biology.

The IncuCyte®platform provides turnkey solutions, comprised of innovative instrumentation, optimized reagents and consumables and sophisticated analytical software, for real-time quantitative analysis of living cells. These solutions provide researchers with the ability to gain new insights and understanding into biological processes via real-time, quantitative analysis of live cells. Placed directly into a standard incubator, the IncuCyte® system automatically collects and analyzes images throughout the course of an experiment while cells remain unperturbed in a physiologically relevant environment.

Multiple T-flasks or up to six 96 or 384 well microtiter plates fit within the system, increasing productivity and allowing different applications and assays to be run simultaneously. More than 2000 images can be collected per hour, converting traditional endpoint assays to a kinetic format for studying movement, migration, apoptosis and other cell behaviors.

“The number and variety of applications enabled by the IncuCyte®system is a testament to its flexibility as an assay platform and the power of combining imaging with the dimension of time,” said Brett Williams, President and CEO, Essen BioScience. “With IncuCyte®, researchers can conceive of and execute experiments that were not previously thought possible, gaining deeper biological insights and understanding.”

The IncuCyte® system consists of an imaging platform that resides in the cell incubator, and a networked external controller that gathers and processes image data, allowing walk-away analysis and remote data connection. Automated data acquisition and visualization tools greatly simplify post experimental analysis.

A searchable database of publications can be accessed here.

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Cell Adhesion AssaysCell adhesion assays are used to quantitate attachment and analyze the molecular mechanisms for extracellular matrix adhesion, cell migration and sensitivity to inhibitors. Find the best cell adhesion assay equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Cell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.Live Cell ImagingLive cell imaging is the study of living cells using microscopes and high-content imaging systems. This technique provides in-depth insight into fast and complex biological processes, by allowing dynamic imaging of living cells instead of acquiring an individual image at a single point in time.Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.Cell BiologyCell biology studies the structure, function, and behavior of cells. Understanding cellular processes is essential for research in areas such as cancer biology, stem cell research, and neurobiology. Techniques like flow cytometry, microscopy, and cell culture enable researchers to explore cellular mechanisms in detail. Browse our peer-reviewed product directory to find the best cell biology tools and equipment, compare products, check customer reviews, and get pricing directly from manufacturers.

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IncuCyte<sup>®</sup> Live-Cell Analysis Platform Cited In Over One Thousand Publications