How to Optimize Assay Automation: Overcome Barriers to Assays Success

Register for our upcoming webinar with laboratory automation experts for advice to improve your assay workflow

10 Apr 2019
Sarah Thomas
Associate Editor

Expert insights

The liquid handling component of assay variability is often underappreciated or not directly measured yet can have a significant impact on data quality. Many laboratories rely on precision alone to assess and mitigate assay variability. However, both the accuracy and precision of the liquid handler need to be measured in order to reduce overall assay variability. To improve data quality even further, the same technology can be applied to study the assay workflow (e.g., process optimization), ensuring successful assay transfer — saving time, money and resources.


In an upcoming SelectScience webinar, automation experts, William Ivory, Senior Scientist and Automation Lead at DiscernDX, and Dr. Nathaniel Hentz, of Artel, present two examples illustrating these principles: optimization considerations for automating a binding protein assay and workflow optimization for a next-generation sequencing (NGS) assay.

Attend this webinar event to:

  • Understand the impact of and how to detect liquid handling variability on assays
  • Understand the importance of studying key liquid handling parameters during the assay optimization process
  • Learn how to improve an assay workflow by studying the assay process
  • Learn the importance of ensuring the performance of your liquid handlers during an assay transfer

REGISTER NOW

The live webinar takes place on Monday, April 29, 2019, at:

  • 16:00 BST
  • 11:00 EDT
  • 08:00 PDT
  • 17:00 CEST

Who should attend:

  • Assay development scientists
  • Assay automation engineers
  • Analytical lab supervisors
  • Assay development lab managers

Scheduling conflict? No matter, register to receive an on-demand link to watch later

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Pipettes and DispensersPipettes and dispensers are essential lab equipment used to dispense measured volumes of liquid accurately. Explore a range of manual and electronic pipettes, including single and multichannel, serological and volumetric pipettes, as well as a range of pipette tips. Bottle-top dispensers are also available for simple and fast solvent dispensing. Find the best pipettes & dispensers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.