“All in One” In Vitro Imaging System

8 Sept 2011
Roger Wayman
Administrator / Office Personnel

Product news

Carestream Molecular Imaging has introduced the new Gel Logic 6000 PRO – a premium system for imaging gel, blots, and plates using multiple modalities including chemiluminescence, UV and multi-wavelength fluorescence, and radioisotopic labels – all in one single, easy to use platform. These modalities can be captured in sequence, which streamlines workflow and offers time savings.

Researchers are no longer limited to 2 or 3 fluorescent channels or restricted to the continuous process of stripping and re-probing blots. The Gel Logic 6000 PRO system comes complete with new Multiplex Analysis Software, a state-of-the art image capture and analysis program that allows researchers to capture, overlay, and analyze data from up to 4 individual layers within an image. This allows for more efficient processes and increases the amount of data that can be extracted from a single experiment.

Other features include:

• A 4.2MP Camera with fixed lens (f/0.95) for rapid and high resolution imaging – this results in crisp imaging and excellent sensitivity for chemiluminescence and fluorescent applications.
• An automated broadband UV trans-illuminator sample platform with 3X zoom for samples (including blots, membranes, and plates) up to 18 x 18 cm.
• LED illumination (including epi-white lights and 5 LED modules) for white light, RGB, and NIR imaging mounted directly to the sample platform, for greater illumination uniformity.

With the Gel Logic 6000 PRO, today’s researchers have the freedom to use the same multi-faceted approach for their in vitro experiments (such as western blotting, DNA gels, chemi blots, fluorescent blots, and more), that they would with microscopy or in vivo experiments.

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Near Infrared SpectroscopyNear-infrared (NIR) spectroscopy measures the interaction of near-infrared light with a sample, including transmission, reflectance and absorbance, facilitating the identification of analytes. Measurements can be conducted using a Fourier-transform near infrared (FT-NIR) spectrometer, while there are also UV-Vis- NIR spectrophotometers that measure a broader spectrum of wavelengths. Find the best NIR spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.UV-Visible SpectroscopyUltraviolet-visible (UV-Vis) spectrophotometers are used to measure the interaction of UV and visible light with a sample, including transmission, reflectance & absorbance. The two major instrument classes are single-beam or double-beam spectrophotometers. More specialized equipment includes colorimeters, spectroradiometers and refractometers. Portable and microvolume spectrophotometers are also available. For the modular spectroscopy lab, explore a range of light sources for combination with a spectrograph/spectrometer and optics. Find the best UV-Vis spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Western BlottingWestern blotting equipment is used to transfer and identify specific proteins within a sample, reveal protein modifications, as well as give a semi-quantitative estimation of their concentration. Western blotting equipment includes all apparatus necessary to transfer proteins from gel to membrane and subsequent processing steps. Protein transfer can be performed by electroblotting with wet, semi-dry and dry transfer systems onto nitrocellulose and PVDF membranes. Blocking, washing and labeling of membranes follows, involving buffers, blocking reagents, blotting / incubation trays, labeling reagents, immunoblotting assays, antibodies and conjugates. Automated equipment for these steps is available to accelerate your lab workflow. Finally, detection and imaging of proteins can be conducted using gel documentation and imaging systems. Find the best western blotting equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.