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A new, informative e-Newsletter for HPLC detection

ESA - A Dionex Company
21 Jun 2007

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ESA Biosciences, a Magellan Biosciences company and leader in quality HPLC detection systems, announced that it has launched an information-based e-newsletter focused on electrochemical detection (ECD) and its applications.

Written by ESA's resident applications experts, The Femtogram is designed as a vehicle to disseminate useful tips and "how to" information about the implementation and application of HPLC electrochemical detection to a wide range of disciplines, including neurochemistry, oxidative metabolism, clinical diagnostics, and general analytical chemistry. The inaugural issue includes an interview with Wyeth, Inc. Principal Scientist, Dr. Chad Beyer, who discusses his ECD work in the Discovery Neuroscience unit at Wyeth in Pearl River, New York, USA.

Regular features in the new publication will include: ECD Innovations - A review of new products and/or innovative applications of ECD; In the Laboratory - An interview with a user of ECD describing how they have successfully implemented ECD in their laboratory; ESA Resources - Profiles of key people standing by at ESA Biosciences to support the use of ECD; Ask Dr. Bruce - A Q&A forum with an expert in ECD solving common ECD issues and Knowledge Links - Useful web addresses providing direct access to the extensive ESA Application and Technical Library.

ESA's Director of HPLC Marketing, Darwin Asa, PhD, remarked, "We see The Femtogram as a key source of information for both new and existing users of electrochemical detection. The body of knowledge accumulated about ECD here at ESA Biosciences over the years is quite extensive across a broad range of topics and techniques. Our customers also have valuable experience to share. We hope the e-newsletter will become a trusted resource to help users benefit from our collective expertise, and provide them with key information for the successful implementation and operation of their ECD systems."

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ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.pH Meters and ElectrodesIon and pH meters are electrochemical equipment used to measure the pH (acidity or alkalinity) or specific ion concentration of a solution. Other meters can also measure the conductivity or dissolved oxygen content of a solution. pH meters, specific ion meters, conductivity meters and dissolved oxygen meters can come as benchtop or portable equipment. A meter’s electrodes can be replaced with easy to clean electrodes or electrodes for difficult media. pH, ion and conductivity meters are typically used in life science research, pharmaceutical testing, food and beverage, environmental and water analysis. Find the best pH meters and electrodes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.pH and Conductivity MetersIon and pH meters, used for electrochemical techniques and measurements, measure the concentration of specific ions using electrodes (probes) and a meter. Features of ph and ion meters to consider include temperature compensation, auto-calibration, adjustable resolution, measurable range and accuracy. Meters can be handheld, portable, benchtop and modular.

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A new, informative e-Newsletter for HPLC detection