Simultaneous Determination of 2- and 4-Methylimidazoles in Beverages Using a FASt® Filter and Shoot Method
22 Dec 2014Traditional methods for the extraction and analysis of 2-methylimidazole (2-MeI) and 4-methylimidazole (4-MeI) in caramel colored beverages 2-MeI and 4-MeI follow several pathways. One option involves tedious ion-pairing extraction, and derivatization paired with GC or GC/MS analysis. A second option uses solid phase extraction (SPE) combined with HPLC or LC/MS-MS detection. This application offers a simple, fast, and cost effective method to simultaneously determine 2-MeI and 4-MeI in beverages.
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Clean Screen® FASt Columns
UCT, Inc.The Clean Screen® FASt column is a novel approach to improved sample preparation for LC/MS analysis. The column employs a one step process to prepare urine samples for analysis of multiple drugs and metabolites. By quickly and efficiently reducing the amount of unwanted matrix and particulates in the final sample, the analysis can proceed with less chance of matrix suppression and LC column clogging.