Application Note: Assay Apoptosis in Magnetically Bioprinted HepG2 Spheroids
14 February 2019

Two-dimensional (2D) cell culture has been used for over a century to investigate a wide range of cellular processes. However, more recent studies have shown that responses in 2D systems can differ significantly from those seen in vivo (Duval et al., 2017).A variety of methods for transforming 2D cultures into 3D spheroids have been devised, but many of these require a long time to form spheroids that can be difficult to handle.