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Analysis of Genotoxic Impurities of Imatinib Mesylate by LC-MS from Early Development to Routine Monitoring

Waters
22 Jun 2017

This application note describes a sensitive and rapid UPLC method, coupled with mass detection, for the quantitative determination of two genotoxic impurities of the Imatinib mesylate drug substance.

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UHPLC and HPLCMass SpectrometryGenotoxicityDrug DevelopmentCancer Research

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