Application Note: Reconstructed Bone (r-Bone™) technology
3 January 2020

In this application note, zPREDICTA describes the Reconstructed Bone (r-Bone™) technology, a patient-derived 3D tissue culture model where the human bone marrow microenvironment is reconstructed in vitro. This technology is capable of supporting long-term survival and expansion of primary multiple myeloma cells and cells from other hematological malignancies, meaning the complex interactions between cells and their microenvironment may be studied.