Application Note: Miniaturization of Illumina Library Preparation in a Shared Facility Setting
11 May 2018

This poster, presented at the AGBT General Meeting 2018, demonstrates the miniaturization of a diverse set of Illumina library protocols on the TTP Labtech mosquito HV liquid handler, and their application to a broad variety of biological sample types. Methods for both RNA and DNA library production and from intact and fragmented samples have been successfully implemented and are widely used. The miniaturization of these protocols has resulted in both significant savings in library production cost, and in a notable increase in the average number of replicates performed by the scientists.