Application Note: Isolating Trace Impurities for Structural Elucidation in a Commercial Fungicide Formulation Using Preparative SFC
28 July 2015
Trace impurities in synthetic products that interact with human end users or may have an undesirable environmental fate are regulated by various government agencies such as FDA and EPA. As a result, impurity separation and their structural identification are important research functions for many industries, including pharmaceutical, agrochemical, food, and consumer products. This application note describes a workflow to achieve full structural elucidation of trace impurities that can be implemented using preparative supercritical fluid chromatography to isolate trace impurities.