Enrichment and sequencing of albumin protein from urine

In this application note, the emphasis is on the importance of identifying and analyzing protein markers in biofluids, particularly in urine for non-invasive disease monitoring. Traditional methods for detecting biomarkers are critiqued for overlooking crucial protein variants and employing complex techniques. The note introduces Quantum-Si's next-generation protein sequencing Platinum^® workflow, highlighting its potential to revolutionize biomarker analysis. A demonstration is provided, showcasing the enrichment of human serum albumin (HSA) from urine and its subsequent sequencing on Platinum^®.