COMET: Streamline hyperplex immunofluorescence at single-cell resolution
20 June 2023

In this application note, Lunaphore Technologies demonstrates how to build an inclusive hyperplex panel to streamline IO research using COMET. Understanding the tumor microenvironment (TME) can aid in tumor classification, identification of biomarkers, and development of targeted therapies. One approach to studying multiple proteins in the TME is multiplex immunofluorescence (mIF), but current assays struggle with long turn-around times and tissue degradation. Lunaphore has developed the COMET, a revolutionary microfluidic instrument that performs hyperplex assays using a sequential immunofluorescence (seqIF) approach. COMET allows researchers to create and customize panels with their off-the-shelf antibodies.