Fragment screening of GPCRs using GCI technology

7 May 2024

G protein-coupled receptors (GPCRs) are notoriously difficult to study, due to their intrinsic protein instability. By utilizing the sensitivity of Grating Coupled Interferometry (GCI) technology combined with non-clog microfluidics, the membrane proteins can be analyzed. Malvern Panalytical, talks with Evotec, a life science company who is committed to advancing drug discovery and development through their collaborations with biotech, pharma, foundations, academia and government agencies. Evotec highlights how it has successfully harnessed GCI for the fragment screening of GPCRs.