Seeing LNP composition in a new light with charged aerosol detection
Wednesday, October 14 at 16:00 BST | 17:00 CEST | 11:00 EDT | 08:00 PDT
Lipid nanoparticle (LNP) therapeutics depend on the precise combination of ionizable lipids, phospholipids, cholesterol, and PEG-lipids to achieve the desired performance. Analyzing these complex formulations can be challenging, requiring analytical methods that deliver both selective separation and reliable quantification across a broad range of lipid chemistries and concentrations.
In this SelectScience® webinar, Adam Kowalczyk, Research Scientist II – Analytical at Acuitas Therapeutics, and Dr. Mateusz Imiolek, Principal Scientist at Waters Corporation, will explore practical approaches for the compositional analysis of LNPs. Drawing on expertise in analytical method development, impurity profiling, chromatography, and gene therapeutic characterization, they will discuss how robust analytical workflows can help support the development and characterisation of LNP-based therapeutics.
Plus, discover how GTxResolve™ RP 230 Å columns, charged aerosol detection (CAD), and an integrated ACQUITY™ workflow can support fast, selective, and reproducible analysis of lipid nanoparticle (LNP) lipid components. Through practical examples, the speakers will demonstrate how optimized chromatography and detection strategies can improve assay robustness, support LNP composition analysis and impurity profiling, and provide the analytical confidence needed to accelerate innovation in lipid nanoparticle development.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
Webinar details
Cost: Free to attend
Location: Online
Duration: 60 minutes
Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available.
Speakers
Who should attend?
- Formulation scientists
- CMC and analytical-development scientists
- Scientists developing LNP lipid composition and impurity methods
- QC-development and method-transfer scientists
- Researchers in biopharma and biotechnology
- CRO/CDMO laboratories working with LNPs, liposomes, mRNA delivery or lipid-based drug products
Featured products
Request Quote for All Products
ACQUITY Premier System
WatersAlong with the reliability, ruggedness, high quality, and configuration flexibility you expect from the ACQUITY™ UPLC™ PLUS Series, the Waters™ ACQUITY Premier System delivers a step change in chromatographic performance, lab efficiency, and risk control.
GTxResolve SEC Columns
WatersAccelerate early research, development, & release testing of GTx drug substances and products
Empower Software Solutions
WatersRun samples and produce meaningful results without downtime with Empower Software Solutions, comprised of Waters industry-leading Empower Chromatography Data System (CDS) and Empower Lab Management System (LMS).
What will this webinar cover?
- Why multiple LNP lipid classes create different separation and detection challenges
- How GTxResolve RP 230 Å surface chemistry and mobile-phase conditions can tune selectivity
- How CAD supports analysis of lipid components with limited UV response
- How ACQUITY™ and Empower™ connect acquisition, calibration, processing, and reporting
Join the webinar to get answers to these questions:
- Why do different LNP lipid classes pose distinct separation and detection challenges?
- How can GTxResolve™ RP 230 Å surface chemistry tune selectivity?
- Which mobile-phase conditions improve LNP lipid separation?
- How does CAD analyze lipid components with limited UV response?
- How do ACQUITY™ and Empower™ integrate acquisition, calibration, processing, and reporting?