CLINICAL24: Can endotyping unlock precision medicine for sepsis and critical illness?

Tuesday, November 10 at 16:00 GMT | 17:00 CET | 11:00 EST | 08:00 PST

Sepsis and critical illness remain among the most complex challenges in modern healthcare. Despite decades of research and numerous clinical trials, many promising therapies have failed to demonstrate consistent benefit across diverse patient populations. Increasingly, biological heterogeneity is being recognized as a key factor underlying these disappointing results.

Endotyping offers a new approach. By identifying biologically distinct patient subgroups with shared underlying biology. Endotyping has the potential to support precision medicine strategies, improve therapeutic targeting, and enhance clinical trial design.

Join our expert speakers in this accredited webinar as they explore the scientific and clinical rationale behind endotyping in sepsis and critical illness. They will give an overview of current endotyping approaches, including transcriptomics and proteomics, examine the evidence supporting their use, and discuss the practical challenges of translating these tools into routine clinical practice.

This educational webinar will provide a balanced perspective on both the opportunities and limitations of endotyping, helping laboratory professionals, clinicians, researchers, and diagnostics developers understand how precision medicine may shape the future of critical care.

Webinar details

  • Cost: Free to attend
  • Location: Online
  • Duration: 60 minutes
  • Format: Expert presentation followed by live Q&A

Can't attend live?

Register today and you will receive access to the recording after the webinar, allowing you to revisit key insights and share learning across your team.

Accreditation statement

SelectScience® is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program.

Certificate of attendance

All attendees who join the live webinar will automatically receive a certificate of attendance, including a summary of key learning outcomes, to support their continuing professional development.

If you watch the on-demand recording, a certificate of attendance can be requested by emailing editor@selectscience.net.

About CLINICAL24

CLINICAL24 is a global initiative dedicated to exploring the challenges facing modern clinical laboratories and highlighting the technologies, expertise, and collaborative approaches helping to improve patient care worldwide.

Speakers

Julian Knight, DPhil, MBChb, MRCP
Julian Knight, DPhil, MBChb, MRCP
Speaker
Professor of Genomic Medicine, University of Oxford
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Narges Alipanah-Lechner, MD, MAS
Narges Alipanah-Lechner, MD, MAS
Speaker
Assistant Professor, Division of Pulmonary and Critical Care Medicine at UCSF
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Dr. Ephraim Tsalik, MD, MHS, Ph.D., FIDSA
Dr. Ephraim Tsalik, MD, MHS, Ph.D., FIDSA
Moderator
Vice President and Chief Scientific Officer, Infectious Disease & Acute Care, Danaher; Adjunct Associate Professor, Duke University School of Medicine; Staff Physician, Durham VA Health Care System
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Lucy Lawrence
Lucy Lawrence
Moderator
Science Editor, SelectScience

Who should attend?

This event is perfect for:
  • Critical care and emergency medicine physicians, advanced practice providers, nurses, and pharmacists
  • Infectious disease physicians
  • Clinical laboratory directors, managers, and laboratory medicine physicians
  • Clinical and translational scientists, including biomarker researchers
  • Clinical trial investigators and study teams
  • Precision medicine and diagnostics R&D professionals

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What will this webinar cover?

  • The impact of biological heterogeneity on patient care, therapeutic development, and clinical trial outcomes in sepsis and critical illness.
  • The principles and methodologies used to define endotypes in critically ill patient populations, including transcriptomic and proteomic approaches.
  • The scientific, operational, and clinical challenges associated with implementing endotyping in routine patient care.
  • The current evidence supporting endotype-driven approaches and their potential role in precision medicine.

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