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The ORCA-Flash4.0 sCMOS Camera for Scientific Imaging

1 Oct 2012
The ORCA-Flash4.0 sCMOS Camera for Scientific Imaging

In this video Ellen Barker, Sales Engineer for Hamamatsu Photonics, tells SelectScience about some of the revolutionary features of the ORCA-Flash4.0 sCMOS camera. With its combination of low noise and high quantum efficiency, the ORCA-Flash4.0 delivers unprecedented sensitivity as well as high dynamic range, blazing fast speeds, large field of view, and excellent resolution—all at once. Interview filmed by SelectScience at EMC 2012.

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Hamamatsu Photonics

Creation of new industries:
Achieving sustainable growth through innovation in science & technology

We, the members of Hamamatsu, consider ourselves a research and development company. As a company, we believe that the only way to achieve sustainable growth is to maintain our technological advantages. It is our job and passion to advance photonic technologies.

Hamamatsu has been working with the Photon for more than 50 years. We have established ourselves as the top company of photoelectron conversion technologies in the world. However, we have yet to fully grasp the nature of the Photon and its potential. The more you study, the more you realize how little you know about the Photon and its applications. That is why we continue to move ahead vigorously with basic research and apply what we learn to photonics.

We realize that pursuing the knowledge of photonics technologies alone, by ourselves, is like reaching for the stars with a ladder. Thus we will work together with colleagues around the world, be they researchers, customers or stockholders, who share our passion and the belief that understanding photonic technologies will lead to broader applications and also generate new industries for the advancement of humankind.

ORCA-Flash4.0 Camera

Hamamatsu Corporation Camera Products Group

Hamamatsu’s brilliantly designed ORCA-Flash4.0 is truly a game changer in the world of scientific imaging. Built on a revolutionary new Gen II sCMOS detector, the ORCA-Flash4.0 is the first sCMOS camera that challenges the performance of all CCD, EM-CCD, and Gen I sCMOS cameras. With its combination of low noise and high quantum efficiency, the ORCA-Flash4.0 delivers unprecedented sensitivity as well as high dynamic range, blazing fast speeds, large field of view, and excellent resolution—all at once. Scientists have used EM-CCDs for very low-light, often high-speed imaging such as TIRF or spinning disk confocal, while they have relied on cooled CCDs for other fluorescence applications such as GFP or multichannel imaging. But the ORCA-Flash4.0 is changing all of that. Now one camera covers a wide range of imaging needs—including localization microscopy, TIRF microscopy, live cell GFP, high-speed calcium ion imaging, FRET, real-time confocal microscopy, and many more. The ORCA-Flash4.0 is a solid piece of camera engineering. It has optimized cooling and outstanding image uniformity across the entire sensor compared to cameras based on Gen I sCMOS technology. Other features include 16-bit A/D converter and multiple external trigger and timing output functions.Applications • Localization microscopy • TIRF microscopy • Live cell GFP • Time lapse fluorescence • Ratio imaging • FRET • High-speed calcium ion imaging • Real-time confocal microscopy • Light sheet microscopy • Morphology • Fluorescence in situ hybridization (FISH) For more information on the ORCA-Flash4.0 please visit our website or request more information at the top of the page.

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The ORCA-Flash4.0 sCMOS Camera for Scientific Imaging