Streamlining lipid nanoparticle characterization with a hands-free approach
14 Oct 2025
The RiboGreen assay is a common method for assessing lipid nanoparticle (LNP) encapsulation efficiency, but it is labor-intensive, error-prone, and lacks insight into therapeutic parameters like mRNA integrity.
Mojca Bavčar, Associate Scientist at Sartorius BIA Separations, introduces the PATfix LNP Switcher®, a 2D chromatography system that enables accurate size estimation and encapsulation efficiency analysis. Discover how this instrument can minimize sample preparation by offering a hands-free approach while delivering valuable therapeutic insights, all within a single assay.
About the company
Sartorius Group
Sartorius is one of the world's leading providers of laboratory and process technologies and equipment. Our innovative products and high-quality services help customers around the globe implement complex and quality-critical processes in biopharmaceutical production and laboratory environments in a time- and cost-efficient way. Our key customers are from the biotech, pharma and food industries, as well as from public research institutes and laboratories. Sartorius operates its own production facilities in Europe, Asia and America, and also has sales offices and local representatives in more than 110 countries. Strongly rooted in the scientific and research communities and closely allied with customers and technology partners, the company is dedicated to its philosophy of "Turning science into solutions" every single day.
At Home Worldwide
Sartorius operates its own production facilities in Europe, Asia, and America and also has sales offices and local representatives in more than 110 countries.
Bioprocess Solutions
Sartorius helps its customers to develop and manufacture biotech medicines reliably, quickly, and economically.
Lab Products & Services
Sartorius products accelerate scientific progress, while enabling dependable, efficient analyses to be performed in labs.
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PATfix LNP Switcher Platform
BIA SeparationsInnovative solution that enables investigation of multiple critical attributes for LNP drug products, without extensive sample preparation or dye requirements.
