PrimaDiag Pipetting Platform for Clean Up and Purification of Nucleic Acids
2 Feb 2016
Purification of PCR and sequencing products are important activities in genomics and must be cleaned of all residual reagents used in the PCR (especially primers). Without this step, the PCR or sequencing reactions performed subsequently give nonspecific products because of a competition and a clash between these different primers. Watch this video to discover how the PrimaMPS 46 can be used for automated medium throughput PCR/sequencing purification.
About the company
PrimaDiag
PrimaDiag, a French company, based at Biocitech (dedicated to Science and biotechnologies) park in the Paris area, develops compact robotics platforms for rapid automation of a large variety of biology protocols and in particular for molecular biology protocols.
PrimaDiag began as an engineering consulting firm in October, 2007 and acquired expertise in the domains of robotics, computer science and biology through various projects realized in France and in Europe.
In 2014, with its acquired experience, PrimaDiag launched its new range of "ACSIA" products offering turnkey solutions, based on a new concept, for the better part of biological protocols. The concept has a set of bases and a set of robotics accessories which can be combined to support a given protocol and managed by a very powerful and user friendly software, PrimaController®II.
Reliable and robust, the ACSIA product line is ideal to prepare of PCR / qPCR, plates, he purification of nucleic acids, the preparation of libraries and the NGS protocol captures as well as any other protocol requiring the handling of liquids.
The ACSIA product line is designed with the best value for money to perform a wide variety of liquid handling protocols with least end user effort and a mastered cost for a rapid return on investment.
All our products are designed and manufactured in France in line with the values which define PRIMADIAG and destined to give you the best service.
PowerfulThe high quality for all your protocols
Reliable Peace of mind with a French quality design and a team at your service
Innovative Another way to apprehend automation
Modular The flexibility for all your needs
Affordable The right price for the highest quality
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Magnetic Work Unit
PrimaDiagModule for handling of magnetic beads combining simplicity and efficiency. This innovative module allows replacing the common gripping systems thanks to its patented technology APIM (Attraction Point by Induced Magnetization). Moreover it is provided with a retaining flange allowing using directly your microplates twisted by the heat of the thermal cycler and avoiding any move.The main goal is to focus the magnetic field generated by a permanent magnet to magnetize some low coercivity ferromagnetic pins. It induces some quick and stable changes from the “magnetized” state to the initial state (demagnetized). It allows the switching On and Off of the magnetic attraction in wells in just a few seconds.The alloy and the special design of the pins allow controlling the strength of the magnetic field along the vertical surface of each well. Then it is possible to create a magnetic beads pellet to a specific position in every well. This attraction point has been chosen to minimize the elution volume and optimize the washing by avoiding the interactions between the tip and the beads pellet.Benefits: Switch On and Off the attraction of the magnetic beads without moving the PCR microplate. The mistakes during the moves of the microplate are eliminated. More cost effective than the solution “passive plate with classic magnets + gripper”. Can maintain firmly the PCR microplate thanks to its retaining flange. This component allows flattening the microplate which can be twisted after getting out the thermal cycler. The pipetting is then facilitated by a better reproducibility of the position of the wells (impossible with a gripping system). Compliant with the most of the clean-up and isolation kits in the market. Compliant with the most of the PCR microplates (skirted, semi-skirted or no skirted). Module managed by a simple and powerful software which facilitate the programming for the end user. A simple On/Off command is sufficent to attract/free the beads. Allows a low elution volume and some optimized washing.
