SelectScience InterviewsClinical Diagnostics

Personalized approaches to sepsis management

16 Jan 2025
Personalized approaches to sepsis management

Find out how the management of sepsis can be personalized for patients in this presentation from the 2024 World Sepsis Congress Spotlight: Unmet Need in Sepsis Diagnosis and Therapy. Topics discussed in this video include how ARDS (Acute respiratory distress syndrome) treatment can be personalized, the use of macrolides in CAP (Community-acquired pneumonia), the TREM-1 pathway, and how immunoparalysis in response to sepsis can be reversed.

00:00:00 Introduction
00:00:44 Bruno Francois, Dupuytren University Hospital, France – TREM-1 Pathway
00:11:41 Carolyn Calfee, University of California, San Francisco Medical Center, USA – ARDS: Room for Precision Treatment?
00:25:48 Sara Cajander, Amsterdam UMC, The Netherlands – Reversal of Immunoparalysis
00:35:29 Michael Niederman, Weill Cornell Medicine, USA – Macrolides for Community-Acquired Pneumonia
00:46:26 Alexander Vlaar, Örebro University Hospital, Sweden – Modulation of Complement
01:00:41 Q&A

About the company

Global Sepsis Alliance

The Global Sepsis Alliance (GSA) is a non-profit charity organization with the mission to provide global leadership to reduce the worldwide burden of sepsis. The GSA is the initiator of World Sepsis Day on September 13 and World Sepsis Congress, a series of free online congresses bringing knowledge about sepsis to all parts of the world, among other initiatives.

The GSA works closely with its over 120 member organizations from all over the world – patient advocacy groups, professional societies, healthcare authorities, and governments – to implement changes on how sepsis is prioritized, diagnosed, and treated all around the world, as laid out in the WHO Resolution on Sepsis.

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Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.SepsisSepsis is a life-threatening response to infection causing organ dysfunction. Research focuses on early detection, biomarkers, and therapies to reduce mortality. Explore tools for sepsis diagnostics and analysis in our peer-reviewed product directory, including detection kits and biomarkers.World Sepsis Congress SpotlightSelectScience is honored to host session from the 2024 World Sepsis Congress Spotlight, in collaboration and support of the Global Sepsis Alliance. Watch these open access presentations, talks and discussions to understand the current situation around laboratory sepsis diagnostics, sepsis therapy and management, and the global sepsis agenda.