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Pall Presents Filtration and Sample Prep Technologies for Lab Automation

Pall Life Sciences - Laboratory, Food, Beverage

24 Feb 2015

Pall Presents Filtration and Sample Prep Technologies for Lab Automation

Learn about the range of Pall Life Sciences products for purification and sample preparation. The unique AcroPrep™ Advance96- and 384-well filter plates are ideal for applications including lysate clearance, DNA binding, multiplexing, and protein purification. Advance Centrifugal Devices enable sample volumes ranging from 500 µL to 60mL, and Acrodisc® Syringe Filters can be used for HPLC, UHPLC and dissolution testing.

About the company

Pall Life Sciences - Laboratory, Food, Beverage

Pall is the largest and most diverse filtration and separation company in the world, and the global leader in the development of new filtration, separation, and purification technologies. The breadth of our product line and scientific resources make us uniquely qualified to deliver the best product technologies for each application we support.

From the discovery and development stages of new drugs, through production and delivery of therapies, Pall Life Sciences provides dependable, high-performance products that expedite and simplify your processes. We are committed to providing many sample preparation and detection tools used in basic research, genomics, proteomics, ADMETox, and combinatorial chemistry applications including scalable chromatography, tangential flow filtration, and sterile filtration products; sample prep products for pharmaceutical QC; filter plates for sample prep and detection; and a new line of lab water purification systems.

For the laboratory, Pall provides products that are:

Optimized: Pall's extensive knowledge and long history of developing uniform membrane materials (lot-to-lot) ensure consistent, reproducible results.
Scalable: Choose from a wide variety of device configurations for processing single or multiple samples from benchtop to high throughput.
Automation Compatible: Pall's high-throughput products are configured to fit standard lab robotic equipment.

Pall's Laboratory Technical Support team provides global, 24-hour-a-day, live technical support. From assisting with routine processes to guiding proper product selection, Pall can help you realize the full potential of your application.

Pall also supplies OEM Solutions for a range of applications in the life sciences, biopharmaceutical, and medical marketplaces.

4.6/5.0

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Links

Pall Life Sciences - Laboratory, Food, Beverage Company website

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Acrodisc® PSF 0.2 µm Syringe Filters
Pall Life Sciences - Laboratory, Food, Beverage
Acrodisc PSF syringe filters are available in many membrane types, sizes, and packaging configurations to fit all applications. These are the only syringe filters to receive Caliper Life Sciences Automation Certified guarantee, providing: Smooth operation and worry-free performance in automated applications with smooth filter-to-filter release, consistent turret advancement, exceptional housing strength, and strict outside filter geometry. Best protection for HPLC columns – extend column life as much as 46 times. Maximum throughput with the GxF multi-layer prefilter.
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Acrodisc® Syringe Filters with PTFE Membrane
Pall Life Sciences - Laboratory, Food, Beverage
Exceptional chemical and temperature compatibility Ideal for filtration of gas and/or organic solvents. Prevent spurious peaks on chromatograms for accurate experimental results. HPLC certified for low levels of UV-absorbing extractables. Prevents "air bubble" lock in sample vials with 13 mm minispike outlet. 4 mm device offers the lowest sample hold up.
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Acrodisc® WBC Syringe Filter
Pall Life Sciences - Laboratory, Food, Beverage
Pall Life Sciences' Acrodisc WBC premium syringe filter is an innovative filtration device designed specifically for use in the capture and recovery of Leukocytes and the separation of red blood cells. The Acrodisc WBC filter contains Pall's patented Leukosorb media. Leukosorb is a fibrous matrix that uses a multimodal approach of size exclusion and adsorption to capture and recover leukocytes from whole blood samples while allowing Red Blood Cells (RBCs) and platelets to flow through the membrane. With the Acrodisc WBC, the uniquely designed filter does all the difficult capture work, resulting in more efficient white blood cell separation as compared to Buffy Coat density gradient methods. The Acrodisc WBC yields greater cell capture and recovery with less sample compared to larger filter formats and also exudes very low hold up volume as compared to larger white blood cell isolation filters (hold up volume Applications: Antigenic specificity Antigen modulation studies Cell receptor analysis Lymphocyte recovery for cell therapy Stem cell research applications
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AcroPrep™ Advance 96-Well Filter Plates for DNA Purification
Pall Life Sciences - Laboratory, Food, Beverage
Maximum Yields of High Quality DNA. Optimized for maximum binding yield of DNA from a variety of sample types New well geometry results in reduced hold-up volume and higher recovery of DNA New outlet tip geometry provides direct flow of samples into receiver plate without concerns of crosscontamination Enhanced membrane ensures high yields of contaminant-free DNA for downstream applications Manufactured in accordance with SBS guidelines, allowing entire DNA purification process to be performed on automated equipment
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AcroPrep™ Advance 96-Well Filter Plates for Multiplexing
Pall Life Sciences - Laboratory, Food, Beverage
Superior Bead Recovery and Low Levels of False Positives Ensure Assay Reproducibility. Smooth well wall provides efficient bead recovery, ensuring reproducible results lot after lot High performance membrane does not trap microspheres in the membrane matrix In serological assays, Supor® membrane effectively removes IgG complexes, thus reducing nonspecific reactivity of the microspheres and reducing false positives New well design results in faster, more uniform filtration rates across the plate with reduced hold-up volume New outlet tip geometry minimizes sample leakage and loss during incubation steps so that acquisition times are not affected Intrinsic plate and membrane properties minimize target loss from non-specific binding
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AcroPrep™ Advance 96-Well Filter Plates for Solvent Filtration
Pall Life Sciences - Laboratory, Food, Beverage
Robust Chemical Resistance Provides Compatibility with Harsh Organics. Chemically resistant materials provide a stable platform to process samples in organic solvents Inert materials of construction ensure complete recovery of samples and low non-specific binding New well design results in faster, more uniform filtration rates across the plate and reduces hold-up volume Innovative outlet tip geometry provides direct flow of samples into receiver plate without concerns of cross-contamination
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AcroPrep™ Advance Filter Plates
Pall Life Sciences - Laboratory, Food, Beverage
AcroPrep™ Advance filter plates are the newest edition to Pall’s filter plate family. New sealing technology and advanced tip design make these the first choice in critical sample prep applications. Aplications: Lysate Clearance DNA purification Protein purification Multiplex assays Aqueous filtration Particulate removal Size exclusion Bead-based assays Neonatal screening Flow cytometry Solvent filtration Concentration, purification and desalting of proteins and nucleic acids Features: Smooth well design – Provides consistency in filtration times, as well as efficient sample and bead recovery Optimized outlet tips – Minimizes sample leakage during incubation steps and reduces the presence of hanging drops following filtration New well geometry – Results in faster, more uniform filtration rates across the plate, thereby improving well-to-well, plate-to-plate and lot-to-lot consistency 100% visual inspection – Ensures each well has proper membrane placement and is free from debris Automation compatible – Manufactured in accordance with SBS guidelines, allowing plates to be run in manual, semi-automated and automated processes
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Jumbosep™ Centrifugal Devices
Pall Life Sciences - Laboratory, Food, Beverage
Convenient and reliable concentration, purification, and diafiltration of 20 to 60 mL biological samples with Pall Life Science's Jumbosep Advance Centrifugal Devices Features of the Macrosep Advance Centrifugal Devices: • Typically concentrates 60 mL sample volumes to 5 mL in 30 minutes. • Provides high recoveries, typically > 90%. • Low protein-binding Omega membrane and polypropylene housing minimize losses due to non-specific binding. • Versatile Omega membrane is available in a variety of MWCOs. • Built-in deadstop prevents spinning to dryness. • Unique sealing mechanism prevents retentate leakage and filtrate contamination. • Economical. Sample reservoir and filtrate receiver can be sanitized or autoclaved, and reused. The Jumbosep centrifugal devices replace dialysis, chemical precipitation, and lyophilization in the following applications: • Concentrating and desalting proteins. • Exchanging buffer or removing salt from chromatography eluates and gradient fractions. • Separating biomolecules from cell culture supernatants. • Concentrating or removing viruses. • Performing crude fractionation of dilute protein mixtures. • Removing debris and particulates from cell lysates.
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Macrosep® Advance Centrifugal Devices
Pall Life Sciences - Laboratory, Food, Beverage
Quickly concentrate up to 20 mL of biological sample Pall Life Sciences Macrosep Advance Centrifugal Devices Features of the Microsep Advance Centrifugal Devices: • Rapidly concentrates 20 mL sample volumes to 0.5 mL. • Provides high recoveries, typically > 90%. • Low protein-binding Omega membrane and polypropylene housing minimize losses due to non-specific binding. • Versatile Omega membrane is available in a variety of MWCOs. • Built-in deadstop prevents spinning to dryness. • Color-coded for easy identificationApplications of the Microsep Advance Centrifugal Devices: Ultrafiltration • Concentrate and desalt proteins. • Exchange buffer or remove salt of chromatography eluates and gradient fractions. • Recover proteins or other molecules from cell culture supernatants. Microfiltration • Remove particulate from aqueous solutions and clinical samples.
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Microsep™ / Macrosep® Advance Centrifugal Devices
Pall Life Sciences - Laboratory, Food, Beverage
Pall centrifugal devices simplify common nucleic acid and protein handling procedures, replacing traditional separation techniques such as column chromatography, preparative electrophoresis, dialysis, gradient centrifugation, and more. Available in various membrane types to meet your application needs.
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Nanosep® & Nanosep MF Centrifugal Devices
Pall Life Sciences - Laboratory, Food, Beverage
Simple, reliable concentrating and desalting of 50 to 500 µL samples. Ensures rapid processing of samples. Typical recoveries are greater than 90%. Available with low protein binding Omega™, Bio-Inert®, and GHP membranes. A wide range of MWCOs, color-coded for easy identification. Constructed of low-binding polypropylene. Ultrasonically welded seals prevent bypass or seal failure. Fits standard centrifuge rotors that accept 1.5 mL tubes.
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