IP-One HTRF® Cell-Based Assay
18 Mar 2009
This video describes the Gq-protein activation pathway, which regulates the production of inositol-1-phosphate (IP1) a specific second messenger. Based on HTRF® its proprietary technology, Cisbio has developed a unique IP-One cell-based assay to assess this accumulation.
About the company
Cisbio Bioassays
Cisbio Bioassays is a privately held life sciences company committed to improving human healthcare. With more than 30 years of experience in in vitro diagnostics and drug discovery, we provide creative technological solutions and partnerships to the global scientific community. Our portfolio of over 460 proprietary assays and reagents is used by pharmaceutical, biotechnology, academia and contract research organizations worldwide to help generate effective therapies.
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IP-One HTRF® Assay
Cisbio BioassaysIP1, a downstream metabolite of IP3, accumulates in cells following Gq recepetor activation and is stable in the presence of LiCl making it an ideal GPCR (Gq) functional assay. Cisbio developed and patented a highly accurate HTRF assay for measuring IP1 in 96-, 384- and 1536-well formats providing for a HTS compatible assay.
