Dr. Jude Fitzgibbon, Barts Cancer Institute - Part 2: Understanding the Molecular Evolution of AML

In this video Dr. Jude Fitzgibbon, Barts Cancer Institute, Queen Mary University of London discusses his work investigating the molecular evolution of familial Acute Myeloid Leukemia (AML). He explains how his laboratory has investigated clinical heterogeneity between families involving at least three inherited gene mutations that can result in familial leukemia. Jude tells SelectScience how this work has implications for the clinical management of these families and how exome sequencing will enable more personalized treatment of familial AML by identifying additional co-operating mutations.