Chemicon's cloned human kappa-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant kappa expression on the cell surface and contains high levels of the promiscuous G protein Galpha15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists and antagonists of the kappa receptor.
Chemicon's cloned human--2A-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant alpha2A expression on the cell surface and contains high levels of the promiscuous G protein Galpha15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between-alpha2A and its ligands.
Chemicon's cloned human S1P3-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant S1P3 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway.
Chemicon's cloned human EP1-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant EP1 expression on the cell surface and contains high levels of the promiscuous G protein Galpha15 to enhance coupling of the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between EP1 and its ligands.
Chemicon's δ membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of agonists and antagonists at δ. The membrane preparations exhibit a Kd of 1.12 nM for [3H]-DADLE. With 0.9 nM [3H]-DADLE, 10 µg/well δ Membrane Prep typically yields greater than 4-fold signal-to-background rati…
Chemicon's D3 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of antagonists of D3 interactions and its ligands. The membrane preparations exhibit a Kd of 0.1 nM for [125I]-Iodospiperone. With 5.0ug/well D3 membrane prep and 0.1 nM [125I]-Iodospiperone, a greater than 4-fol…
Chemicon's glucagon receptor membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of antagonists of glucagon receptor interactions and its ligands. The membrane preparations exhibit a Kd of 3.09 nM for [125I]-glucagon. With 1 nM [125I]-glucagon, 5 or 10 μg/well glucagon receptor…
EMD Millipore's Ghrelin Receptor membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of antagonists of ghrelin interactions and its ligands. The membrane preparations exhibit a Kd of 0.32 nM for [125I]-ghrelin. With 0.1 nM [125I]-ghrelin, 5 μg/well Ghrelin Receptor Membrane Pre…
The AcroPrep™ Advance filter plates for lysate clearance effectively remove cellular debris quickly and allow for the use of additional wash steps to maximize sample recovery. Filtration can be accomplished by either vacuum manifold or centrifugation, ultimately maximizing your choice in protocols. The purification of biomolecules (DNA, RNA and proteins) from prokaryotic and eukaryotic cell lines can be problematic. The AcroP…
This ready-to-use kit is intended for the purification of poly (A)+ mRNA from cultured cells, animal and plant tissues, and is used together with the PickPen magnetic tool. Each purification takes only 10 minutes. The kits are configured to accommodate different sample amounts.
The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…
The ProteoPlex™ 16-Well Murine Cytokine Array Kit is designed for multiplex detection and measurement of 10 important mouse cytokines in parallel from up to 15 experimental samples. The 10 analytes measured in the kit are pro- and anti- inflammatory cytokines important for the study of immune system regulation and diseases such as asthma and arthritis. Each well on the slide contains a microarray of spotted antibodies with fou…
The ProteoPlex™ 16-Well Human Cytokine Array Kit is designed for multiplex detection and measurement of 12 important human cytokines in parallel from up to 15 experimental samples. The combination of advanced surface chemistry, well-characterized capture agents, and a highly-sensitive fluorescence-based detection system provides a robust method for comparing relative cytokine abundance or cytokine quantification in serum sampl…
Cellomics® Content Addressed Storage (CAS) Module for EMC Centera™ is an HCS Applications Server plug-in that provides an interface to the EMC Centera content addressed storage system. Centera is EMC’s newest storage platform specifically designed to work with large volumes of fixed content information, such as the many terabytes of images generated by HCS instrumentation. The CAS Module allows HCS image data to be seamlessly…
Low Cell Binding surface is based on a polymer presenting a phosphorylcholine moiety to the cells, thereby mimicking the surface of a cell membrane Biologically inert and biocompatible Useful for: Culture of oocytes, e.g. Xenopus Colony assay for cancer cells Isolation of macrophages Detection of cytokines and other cell secretions Culture of embryonic bodies Culture of spheroids, e.g. HepG2 Details Low Cel…
Quick and Easy Antibody Quantitation:With its simplicity and ease of use, Guava’s new RapidQuantTM IgG Kits have raised the bar for IgG titering assays. Designed to be time-saving, labor-saving and money-saving, Guava’s RapidQuant kits eliminate the most tedious, laborious portions of antibody titering methods with Guava’s signature ease of use. • Robust, rapid and highly reproducible • Relevant quantitative range • Quantifies…
Millipore’s FlowCellect™ Multi-Color DNA Damage Response Kit is designed to enable a researcher a quick and easy way to detect the phosphorylation state of ATM, SMC1 and Histone H2A.X by flow cytometry. Millipore’s FlowCellect™ Multi-Color DNA Damage Response Kit was developed and tested using the DNA damaging reagent, Etoposide, in HeLa cells as a model system but the kit can be used with other human cell lines to determine…
The Nano-Plotter™ series are ideal for generating high-quality spots by non-contact dispensing of sub-nanolitre volumes. The highly versatile “drop on demand” piezoelectric technology allows the placement of drops onto a variety of substrates with outstanding precision, and also the mixing of samples into pre-filled cavities to run nano-assays. These compact instruments are your ideal solution for the development and producti…
The Thermo Scientific™ DXR™xi Raman imaging microscope pushes Raman microscopy to the next level High performance chemical imaging is now accessible to all, accelerating research for new and experienced users alike. Optimize imaging parameters in real-time to visualize your data faster using the comprehensive Thermo Scientific™ OMNIC™xi imaging software. With its automatic feature recognition and powerful component identifica…
1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard diluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 4 apoptosis markers in cell and tissue lysates
1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard diluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 5 apoptosis markers in cell and tissue lysates
1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard dilluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 4 apoptosis markers in cell and tissue lysates
Providing Ultimate Sensitivity for Vapor Phase and Particulate Isocyanates.The ASSET EZ4-NCO dry sampler for isocyanates is the easy-to-use sampler offering the ultimate sensitivity for collection & measurement of vapor phase and particulate isocyanate monomers and oligomers.Key Features and Benefits:• Ability to achieve reliable, low detection limits• Only device to measure vapor phase and particulate isocyanates• Sampling fo…
The Ziath Linear Rack Scanner Version 2 is for use with the DataPaq™ Express, Deep Focus, High Speed and Multi-Rack Scanners. It is simply attached to the scanner using a bracket with a magnetic place holder. No assembly of the linear scanner is required, in addition the DataPaq™ Linear Rack Barcode Scanner is very simple to attach to existing 2D scanners, and offers easy installation. It can be attached to any side of the Da…
Neptune™ HRP Conjugate Stabilizer preserves the activity of HRP-protein conjugates. This HRP stabilizer can be used to store concentrated stock HRP conjugates, reconstitute lyophilized conjugates, and dilute HRP conjugated antibodies to their useful working titer in ELISA tests and immunology-based techniques.Neptune™ HRP Conjugate Stabilizer is especially suited for ELISAs using anti-IgG HRP conjugates within traditional ant…
