VectaPlex™ Antibody Removal Kit (VRK-1000)

10 Mar 2026

This white paper introduces the VectaPlex Antibody Removal Kit, an innovative solution designed to simplify multiplex immunohistochemistry, immunofluorescence, and tyramide signal amplification workflows. Traditional antibody stripping approaches, such as heat-induced epitope retrieval, can damage tissue morphology and compromise antigenicity. VectaPlex provides a gentle and efficient method for removing antibodies and detection reagents between staining rounds while preserving tissue integrity. The workflow enables sequential multiplex staining using standard reagents and chromogenic substrates, allowing researchers to analyze multiple biomarkers in a single tissue sample with improved reliability and reduced optimization.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ImmunohistochemistryImmunohistochemistry (IHC) is a technique used to detect specific proteins in tissue samples by using antibodies that bind to target antigens. IHC is widely applied in pathology, immunology, hematology and cancer diagnostics. Explore IHC tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.MultiplexImmunofluorescenceSpatial Biology