Using the Mithras LB 943 for High-Performance Time-Resolved FRET Analysis
18 Nov 2016This application note describes the validation of the Mithras2 LB 943 Monochromator Multimode reader with the Transcreener® GDP TR-FRET Red assay from BellBrook Labs. The Mithras² LB 943 is a high-end microplate multimode reader based on monochromator technology with excellent performance. Characterized by its sensitivity and robustness, especially in luminescence and BRET measurements, the reader supports all important reading technologies.
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Transcreener® GDP GTPase Assays
BellBrook LabsThe Transcreener® GDP GTPase Assay Kit directly measures GDP produced during GTP hydrolysis in a homogeneous mix‑and‑read format—no coupling enzymes needed. Compatible with GTPases, GAPs, and GEFs, it supports FP, FI, and TR‑FRET readouts using far‑red tracers to reduce interference. HTS‑ready with excellent sensitivity (Z′ ≥ 0.7), it streamlines screening and profiling workflows.