Uncover new drug targets through cell metabolism
21 Dec 2022Looking at the genes, proteins, and pathways that modulate energy metabolism is a promising new avenue for developing novel therapeutic strategies for a broad range of diseases. In this eBook, Agilent Technologies provides examples of metabolic targets impacting key disease areas, including cancer, immuno-oncology/immunotherapy, neurodegenerative diseases, diabetes, cardiovascular and acquired metabolic disorders.
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Seahorse XF Cell Mito Stress Test Kit
Agilent TechnologiesThe Agilent Seahorse Cell Mito Stress Test kit is the widely recognized, well accepted standard assay for assessing mitochondrial function. Multiple parameters are obtained in this one assay including, basal respiration, ATP-linked respiration, maximal and reserve capacities, and non-mitochondrial respiration. The assay provides insights into the mechanism of mitochondrial dysfunction and allows users to investigate functional differences among cell types, drug candidates, and genetic or biochemical interventions. Each kit contains the material sufficient for six full plate tests and is available in two packaging sizes. The XF kit is for use with the Agilent Seahorse XF Pro, XF96/XFe96 and XFe24 Analyzers. The XFp kit is for use with the Agilent Seahorse XF HS Mini and XFp Analyzers.