ResourceClinical Diagnostics
The choice of serum free light chain analysis method could potentially have clinical consequences for myeloma patients
7 Sept 2026This case study summarizes clinical findings from a comparative evaluation of Binding Site’s Freelite® and Siemens’ N Latex FLC serum free light chain assays in patients with plasma cell disorders. Discover how discrepancies between assay results influenced diagnosis, disease monitoring, and treatment decisions, including cases involving delayed therapy, misclassification of disease progression, and serious patient outcomes. Plus, learn about the clinical implications of free light chain assay selection and the importance of accurate monitoring in the management of multiple myeloma and related disorders.
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Resource type: Case study
Page count: 2
Read time: 3 mins
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Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Myeloma
