Streamlined Method for Pesticide Residues in High-Lipid Food Samples using QuEChERS Extraction, LipiFiltr® Cleanup and UHPLC-MS/MS Analysis

This application note outlines the performance benefits achieved using the new LipiFiltr^® cartridge in applications involving multi-class, multi-residue analysis for a wide range of pesticides (n=189) in complex, high fat samples. The easy-to-use LipiFiltr^® push-through purification cartridge was designed to remove lipids from acetonitrile extracts. Samples are extracted using a standard QuEChERS procedure and an aliquot of the supernatant is simply pushed through the LipiFiltr^® purification cartridge using a disposable syringe. The purified extract is collected in an autosampler vial and analyzed by UHPLC-MS/MS. The ability to obtain significantly cleaner extracts, ease of use, and time and cost savings make the new LipiFiltr^® push-through cartridges an attractive cleanup option for laboratories conducting pesticide residue analysis in complex fatty samples.