Sorting of rare SARS-CoV-2-specific B cells

3 Mar 2022

In this application note, the MACSQuant® Tyto® is it is used to sort rare antigen-specific B cells with high purities. A combination of pre-enrichment using the REAlease CD19 MicroBead Kit and the MACSQuant Tyto Cartridge HS is used to speed up the sorting process.

MACSQuant® Tyto® Cell Sorter

Miltenyi Biotec B.V. & Co. KG

The MACSQuant ® Tyto ® is a next generation, benchtop cell sorter equipped with 3 lasers, which allows for high speed, 10-parameter cell sorting. A unique feature of the instrument is the fact that the actual sorting process takes place exclusively within a single-use, disposable and fully closed system: the MACSQuant Tyto Cartridge. The closed cartridge provides full operator safety and eliminates the risk of sample contamination and carry-over.

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Sorting of rare SARS-CoV-2-specific B cells