Scaling with organoids: Implementing patient-derived organoid models in high-throughput workflows

7 Aug 2025

Producing patient-derived organoids (PDOs) at scale has become a major bottleneck in adopting these models for high-throughput and repeat-use applications such as pooled CRISPR screening, hit-to-lead screening, and compound screening. Traditional culture methods are slow, labor-intensive, and often yield inconsistent organoid models, making it difficult to meet the demands of these applications.

In this eBook, we explore these challenges in depth and share proven strategies to help you scale up your organoid research. Learn how to obtain consistent, high-quality PDOs and integrate them seamlessly into high-throughput assays.

CellXpress.ai Automated Cell Culture System

Molecular Devices®

The CellXpress.ai™ Automated Cell Culture System is an AI-driven cell culture innovation hub that gives your team total control over demanding cell culture feeding and passaging schedules—eliminating time in the lab while maintaining a 24/7 schedule for growing and scaling multiple stem cell lines, spheroids, or organoids.

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Scaling organoid production with automation