ResourceLife Sciences
Rapid Assessment of Size Changes Using the Scepter™ Cell Counter can be Predictive of Cell Death
18 Jul 2013The process of programmed cell death or apoptosis is an essential component in many biological processes and is therefore the focus of much research. Initial studies revealed that reduction in cell volume was an early morphological change during apoptosis. Recent studies have shown that this cell shrinkage is not simply a passive consequence of other apoptotic events, but is a key driver of apoptotic signaling, mediated by the cell’s machinery for homeostatic regulation. In this application note read how the Scepter™ handheld, automated cell counter can be used to measure cell size as an indicator of apoptosis.
Links
Tags
Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ApoptosisApoptosis, or programmed cell death, is a vital process for healthy tissues and is key to our understanding of disease mechanisms like cancer and neurodegeneration. Research tools enable apoptosis detection, quantification, and analysis. Browse products for apoptosis research in our peer-reviewed product directory.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.