Proteomic Analysis of Acetaminophen Toxicity in 3D Human Liver Microtissues

1 Sept 2014

This poster demonstrates an applied novel mass-spectrometric approach - Hyper Reaction Monitoring (HRM) – to quantify changes in protein expression in 3D InSight Human Liver Microtissues exposed to acetaminophen.

3D InSight™ Human Liver Microtissues

InSphero

Discover the 3D InSight™ Human Liver Microtissues: the gold standard for Hepatotoxic screening. Pharma-validated co-culture models offer 2x higher DILI prediction sensitivity than 2D hepatocytes. Features pooled PHH from male/female donors co-cultured with Kupffer cells and LECs, 28-day viability, in 96-well format. Includes 50mL 3D InSight™ Liver Maintenance Medium. Check the bi-weekly production schedule online. 

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Proteomic Analysis of Acetaminophen Toxicity in 3D Human Liver Microtissues