Profiling Analysis of Mono-, Di- and Tri-phosphate Nucleotides Using Capillary Ion Chromatography Mass Spectrometry
6 Oct 2013There have been extensive studies of using nucleoside analogs as prodrugs in anti-cancer, anti-viral and immunosuppressive therapy, and monitoring of their activated nucleotides metabolites is of paramount importance to understand the pharmacology. This poster evaluates a quantitative method for targeted metabolic profiling analysis of mono-, di-, and tri-phosphate nucleotides using capillary ion chromatography tandem mass spectrometry (Cap IC-MS-MS).
Related Products
Request Quote for All Products
Finnigan TSQ Quantum Discovery MAX
Thermo Fisher ScientificThe NEW Finnigan TSQ Quantum Discovery MAX: Extraordinary Value The high-performance, ultra compact benchtop Finnigan TSQ Quantum Discovery MAX incorporates innovative new technology for increased sensitivity, precision, ruggedness, and reliability. It is principally designed for high-productivity environments such as environmental, clinical and drug discovery laboratories. With the Ion Max source, the Finnigan TSQ Quantum Discovery MAX addresses the need of these laboratories for more rugged and dependable LC/MS/MS to enable around-the-clock productivity. The combination of our patented HyperQuadEmass analyzer system, high efficiency ion transfer optics, and outstanding ion source roboustness provides precise accurate quantitation even at the lowest levels.