Producing 3D neuronal microtissues for preclinical drug screening using ioGlutamatergic neurons

3D cell culture models using human induced pluripotent stem cells (iPSCs) have emerged as a promising, human relevant model system for the study of central nervous system (CNS) disorders. However, the complexity of iPSC differentiation has hindered adoption of these models for high-throughput drug screening, leaving researchers to rely on 2D models with poor predictive validity. Discover how ioCells™ from bit.bio, generated through opti-ox™ technology, provide a solution by using deterministic cell programming to consistently generate mature human neuronal cells at scale.