ResourceEnvironmental
Optimizing the preconcentration of volatile PFAS precursors: A comparative study of SPME geometries
26 Feb 2026Due to per- and polyfluoroalkyl substances (PFAS) extreme resistance to degradation, these compounds have earned the moniker ‘forever chemicals’. The vast chemical diversity of PFAS types means that no single analytical method is suitable for all compounds.
In this application note, CTC Analytics discusses a comparative study that evaluates two SPME geometries for the analysis of volatile PFAS. The study leverages the full automation capabilities of a PAL RTC System to ensure high precision and reproducibility.
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Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PFASAutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.