Optimizing the preconcentration of volatile PFAS precursors: A comparative study of SPME geometries

26 Feb 2026

Due to per- and polyfluoroalkyl substances (PFAS) extreme resistance to degradation, these compounds have earned the moniker ‘forever chemicals’. The vast chemical diversity of PFAS types means that no single analytical method is suitable for all compounds.

In this application note, CTC Analytics discusses a comparative study that evaluates two SPME geometries for the analysis of volatile PFAS. The study leverages the full automation capabilities of a PAL RTC System to ensure high precision and reproducibility.

PAL RTC

CTC Analytics AG

The PAL RTC with robotic tool change maximizes productivity in analytical and clinical labs.

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