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Obtaining ultrapure water for sensitive PFAS analysis by LC-MS

20 Nov 2024

Discover how the Milli-Q® water purification system is suitable for the most sensitive PFAS analyses by LC-MS/MS. Ultrapure water produced by a Milli-Q IQ 7000 system fitted with a LC-Pak® polisher at the point-of-dispense was tested for 40 PFAS compounds according to the draft EPA 1633 method. None of the 40 compounds tested were detected in the water.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Water PurificationThere are a number of water purification methods available to remove contamination from laboratory water. These systems include demineralization, reverse osmosis, filtration and ultrafiltration. A combination of methods is sometimes necessary to achieve purified water suitable for use in experiments.Ultrapure WaterUltrapure water is the highest purity water and contains the lowest levels of organic and inorganic contaminants, particulates and microorganisms.PFAS
Ultrapure water for PFAS LC-MS/MS analysis - SelectScience resources