NovaSeq X and NovaSeq X Plus Sequencing Systems

18 Mar 2026

In this brochure, Illumina introduces the NovaSeq™ X and NovaSeq X Plus Sequencing Systems, next-generation platforms that delivers transformational throughput for large-scale human genomics and multiomics studies. Discover how these systems can support deeper sequencing, larger sample cohorts, and data-intensive applications, enabling research in cancer, genetic diseases, and beyond, while providing a user-centric design and reduced total cost of ownership for an efficient and accessible sequencing experience.

NovaSeq™ X Series

Illumina

The NovaSeq X and NovaSeq X Plus Sequencing Systems deliver extraordinary throughput and accuracy to perform data-intensive applications at production scale.

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Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
NovaSeq X and NovaSeq X Plus Sequencing Systems