Methionine and Glutamic Acid analyzed with LCMS

24 Mar 2022

Amino acid analysis is generally performed by HPLC along with a time-consuming pre-column derivatization process that is very tedious and adds cost. In this application note, a method is used where the derivatization step is not necessary and the compounds are easily quantified.

Cogent Diamond Hydride™ HPLC Columns

MicroSolv Technology Corp.

Cogent Diamond Hydride HPLC Columns are manufactured with TYPE-C™ silica (silica hydride) and a very small amount of carbon on the surface that adjusts the column hydrophobicity to an important level. This makes these columns have unique separation capabilities for scientists working in LCMS, metabolomics, bioanalytical, amino acids, organic acids, carbohydrates, and very polar small molecules.

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Methionine and Glutamic Acid analyzed with LCMS